Brad Goodner, Ph.D.


Professor of Biology
Edward J. Smerek Chair of Mathematics, the Sciences, & Technology
Director, Center for Scientific Engagement

B.S., Texas A&M University
Ph.D., Purdue University

113 Colton Hall
330-569-5260
This email address is being protected from spambots. You need JavaScript enabled to view it.

I was born and raised in North-Central Texas (apologies in advance for the accent), but I don't wear boots, a ten-gallon hat, or a belt with a big buckle. My academic history has included stints as an Aggie, a Boilermaker, a Tar Heel, a Spider, and now a Terrier (extra points if you can name all the schools). I teach introductory biology, genetics, microbiology, medical microbiology, bioinformatics, and plant physiology. My students and I use a variety of molecular tools to understand how "simple" bacteria do their thing. Specifically, we are interested in how bacteria organize their genomic and metabolic space, and how they interact with their environment and with other organisms. There are two parallel tracks and one overarching umbrella to this work. One track involves the physiological, ecological, and evolutionary analysis of new model microbes, mostly on the soil saprophyte / plant pathogen / opportunistic human pathogen Agrobacterium. The second track is comparative analysis of bacterial genomes and community metagenomes using DNA sequencing and bioinformatics. The umbrella covering these tracks is incorporation of research as part of courses at Hiram College and through outreach to area high schools. These efforts in courses lead many more students into subsequent independent research projects.

For two decades now at two different institutions, I have been working to find new ways to involve my undergrads, high school students, and myself in fun, cutting-edge genomics projects that allow me to merge teaching and research. Over the past several years, I have worked with others to develop national efforts in microbial genome annotation and functional genomics. While I love to share what has worked and what has not worked for me, I freely admit that I am constantly on the lookout for great questions, ideas, and strategies that will move us to another level.

Outside of academia, my life revolves around the 3 women who rule my house – my wife and two teenage daughters. We love to read, cook, garden, travel, and learn together.

Courses

Research Interests

  • Deeper annotation and functional genomics to better understand the biology of Agrobacterium tumefaciens C58. link
  • Annotation of the Streptobacillus moniliformis genome
  • Annotation & analysis of the probiotic Bacillus coagulans GBI-30 genome. link
  • Development of several new genetic model microbial systems (all coming from Hiram projects)
  • Metagenomics analyses of a variety of microbial communities
  • Hiram Genomics Initiative: Bringing research into the undergraduate classroom (787 students in 1795 research contacts)
  • Hiram Genomics Academy: Summer research opportunity for 300 high school students since 2006
  • Hiram Genomics + Spanish Academy: Summer research opportunity for 17 high school students in 2013
  • Hiram Genomics Store: Entrepreneurial science education business launched in 2010

Selected Publications

  • Slater. S., J.C. Setubal, B. Goodner, K. Houmiel, J. Sun, R. Kaul, B.S. Goldman, S.K. Farrand, N. Almeida Jr, T. Burr, E. Nester, D.M. Rhoads, R. Kadoi*, T. Ostheimer*, N. Pride*, A. Sabo*, E. Henry*, E. Telepak*, L. Cromes*, A. Harkleroad*, L. Oliphant, P. Pratt-Szegila, R. Welch, & D. Wood, 2013. Reconciliation of sequence data and updated annotation of the genome of Agrobacterium tumefaciens C58, and distribution of a linear chromosome in the genus Agrobacterium. Applied & Environmental Microbiology 79:1414-7.
  • Chaston, J.M., G. Suen, S.L. Tucker, A.W. Andersen, A. Bhasin, E. Bode, H.B. Bode, A.O. Brachmann, C.E. Cowles, K.N. Cowles, C. Darby, L. de Le´on, K. Drace, Z. Du, A. Givaudan, E.E.H. Tran, K.A. Jewell, J.J. Knack, K.C. Krasomil-Osterfeld, R. Kukor, A. Lanois, P. Latreille, N.K. Leimgruber, C.M. Lipke, R. Liu, X. Lu, E.C. Martens, P.R. Marri, C. Me´digue, M.L. Menard, N.M. Miller, N. Morales-Soto, S. Norton, J-C. Ogier, S.S. Orchard, D. Park, Y. Park, B.A. Qurollo, D. Renneckar Sugar, G.R. Richards, Z. Rouy, B. Slominski, K. Slominski, H. Snyder, B.C. Tjaden, R. van der Hoeven, R. D. Welch, C. Wheeler, B. Xiang, B. Barbazuk, S. Gaudriault, B. Goodner, S.C. Slater, S. Forst, B.S. Goldman, & H. Goodrich-Blair, 2011. The Entomopathogenic Bacterial Endosymbionts Xenorhabdus and Photorhabdus: Convergent Lifestyles from Divergent Genomes. PLoS One 6:e27909.
  • Slater S.C., B.S. Goldman, B. Goodner, J.C. Setubal, S.K. Farrand, E.W. Nester, T.J. Burr, L. Banta, A.W. Dickerman, I. Paulsen, L. Otten, G. Suen, R. Welch, N.F. Almeida, F. Arnold*, O.T. Burton, Z. Du, A. Ewing*, E. Godsy, S. Heisel, K.L. Houmiel, J. Jhaveri, J. Lu, N.M. Miller , S. Norton, Q. Chen, W. Phoolcharoen, V. Ohlin*, Ondrusek*, N. Pride*, S.L. Stricklin, J. Sun, C. Wheeler, L. Wilson*, H. Zhu, & D.W. Wood, 2009. Genome sequences of three Agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria. Journal of Bacteriology 191:2501-11.
  • Ditty, J.L., C.A. Kvaal, B. Goodner, S.K. Freyermuth, C. Bailey, R.A. Britton, S.G. Gordon, S. Heinhorst, K. Reed, Z. Xu, E.R. Sanders-Lorenz, S. Axen, E. Kim, M. Johns, K. Scott, & C.A. Kerfeld, 2010. Incorporating genomics and bioinformatics across the life sciences curriculum. PLoS Biology 8:e1000448.·         Rodrigues, D., B.W. Goodner, & M.R. Weiss, 2010. Reversal learning and risk-averse foraging behavior in the Monarch Butterfly, Danaus plexippus (Lepidoptera: Nymphalidae). Ethology 116:270-80.·         Setubal J.C., P. Dos Santos, B.S. Goldman, H. Ertesvåg, G. Espin, L.M. Rubio, S. Valla, N.F. Almeida, D. Balasubramanian*, L. Cromes*, L. Curatti, Z. Du, E. Godsy, B. Goodner, K. Hellner-Burris*, J.A. Hernandez, K. Houmiel, J. Imperial, C. Kennedy, T.J. Larson, P. Latreille, L.S. Ligon, J. Lu, M. Mærk, N.M. Miller, S. Norton, I.P. O'Carroll, I. Paulsen, E.C. Raulfs, R. Roemer*, J. Rosser, D. Segura, S. Slater, S.L. Stricklin, D.J. Studholme, J. Sun, C.J. Viana, E. Wallin*, B. Wang, C. Wheeler, H. Zhu, D.R. Dean, R. Dixon, & D. Wood, 2009. The genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes. Journal of Bacteriology 191:4534-45.
  • Slater, S., Goodner, B., Setubal, J., Goldman, B., Wood, D., Nester, E.  2008.  The Agrobacterium tumefaciens C58 genome. Chapter 4 in Agrobacterium: From Biology to Biotechnology. Tzfira, T. and Citovsky, V., editors. Springer, New York. pp. 149-181.
  • Latreille, P., S. Norton, B. Goldman, J. Henkaus, N. Miller, B. Barbazuk, H. Bode, C. Darby, Z. Du, S. Forst, S. Gaudriault, B. Goodner, H. Goodrich-Blair, & S. Slater, 2007. Optical mapping as a routine tool in bacterial genome sequencing. BMC Genomics 8:321.
  • Forst, S., & B. Goodner, 2006. Comparative bacterial genomics and its use in undergraduate education. Biological Control 38:47-53.
  • Goodner, B., & C. Wheeler, 2006. Functional genomics: using reverse genetics to test bioinformatics predictions. ASM MicrobeLibrary (peer-reviewed Web site for microbiology teaching resources; winner of 2007 MicrobeLibrary award for best curriculum resource submission).
  • Csonka, L.N., K. O'Connor, F. Larimer, P. Richardson, A. Lapidus, A.D. Ewing*, B.W. Goodner, & A. Oren, 2005. What we can deduce about metabolism in the moderate halophile Chromohalobacter salexigens from its genomic sequence. Chapter 18 in Adaptation To Life At High Salt Concentrations In Archaea, Bacteria, and Eukarya. Gunde-Cimerman, N., A. Oren, & A. Plemenita, eds.  Springer-Dordrecht.
  • Goodner, B., & D. Wood, 2004. Going after the whole genome from two different angles, pp. 292-309 in Agrobacterium tumefaciens: From Plant Pathology to Biotechnology. Nester, E., M.P. Gordon, & A. Kerr, eds. St. Paul, MN: APS Press.
  • Goodner, B., & C. Wheeler, 2004. Genetic and physical mapping of a bacterial genome. ASM MicrobeLibrary (peer-reviewed web site for microbiology teaching resources).
  • Goodner, B., G. Hinkle, S. Gattung, N. Miller, M. Blanchard, B. Qurollo, B.S. Goldman, Y. Cao, M. Askenazi, C. Halling, L. Mullin, K. Houmiel, J. Gordon, M. Vaudin, O. Iartchouk, A. Epp, F. Liu, C. Wollam, M. Allinger, D. Doughty*, C. Scott*, C. Lappas*, B. Markelz*, C. Flanagan*, C. Crowell*, J. Gurson*, C. Lomo*, C. Sear*, G. Strub*, C. Cielo*, & S. Slater, 2001. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. Science 294:2323-2328.

*denotes undergraduate student

 

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